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Vaccine for Malignant Catarrhal Fever?
The annual wildebeest migration - one of the world's greatest spectacles but also a real threat to the livelihood of local farms.
The annual migration of over a million wildebeest across the Serengeti and Maasai Mara is often described as one of the greatest spectacles on earth. However, this natural wonder poses a real threat to the livelihood of local farmers whose cattle are essential to their economic and social welfare.

RESEARCHERS led by David Haig, Professor of Animal Infection and Immunity at The University of Nottingham have already developed a candidate MCF vaccine for use in cattle. The next step is to test it in field conditions. Over the next three years his research team will test the vaccine in Tanzania, develop it further as required and then look to make a new vaccine for a sheep virus which is very similar to the wildebeest virus and causes MCF in livestock in other parts of the world, including Europe, Indonesia, Australasia and the Americas.

Professor Haig, from the School of Veterinary Medicine and Science, said: “The quest for a vaccine for Malignant Catarrhal Fever goes back to the middle of the last century. We have the first successful vaccine candidate and this is eagerly sought by the pastoralists and farmers in Eastern and Southern Africa, who have been lobbying for this for many years. We also have a strategy to develop a vaccine for a related virus causing MCF elsewhere in the world and are delighted that BBSRC/DFID have given us the opportunity to develop this.”

The research project is part of a £13m initiative... to support farmers and families in the developing world.
The research project is part of a £13m initiative funded by the Biotechnology and Biological Sciences Research Council (BBSRC) and the Department for International Development (DFID) to support farmers and families in the developing world.

Professor Haig will be working with experts from Glasgow University, the Moredun Research Institute, in Scotland, and Sokoine University of Agriculture in Tanzania, the Tanzania Wildlife Research Institute (TAWIRI), Tanzania National Parks (TANAPA), Central Veterinary Laboratory, and VETAID, Tanzania.

Agriculture is vital for the livelihoods of 75 per cent of the world's poor. Food demand is predicted to increase by 50 per cent by 2030. The BBSRC and DFID have joined forces to harness the UK's world-class bioscience base to address the challenges posed by livestock diseases and work with developing countries to provide practical and sustainable solutions.

‘Combating Infectious Diseases of Livestock for International Development’ is an initiative made up of 16 projects, involving 16 UK institutions and eight other countries, which over the next four years will look at some of the most prevalent, damaging and costly diseases of livestock in developing countries and work with more than 20 overseas institutes to not only control or prevent these diseases but also to build scientific capacity at a local and national level within these countries to enable them to manage these diseases and apply new findings and technologies to other disease areas, in both livestock and humans.

‘Combating Infectious Diseases of Livestock for International Development’ is an initiative made up of 16 projects, involving 16 UK institutions and eight other countries, which will look at some of the most prevalent, damaging and costly diseases of livestock in developing countries.
The projects will also offer significant benefits to farmers and consumers in the UK — animal diseases do not respect national boundaries and are estimated to have cost the UK economy over £15 billion over the past 15 years. Several of the diseases being tackled by the initiative are spreading across countries and continents and some are already a direct threat to UK livestock such as Foot and Mouth disease and Bluetongue virus. New technologies developed as part of this research could also be transferable for use to combat other animal diseases and possibly human ones too.

Science and Innovation Minister Lord Drayson said: “This collaboration demonstrates the UK's determination to share our world-leading science in the search for improved treatments and diagnostic tools in animal health. Animal disease is a deadly threat that leaves no corner of the Earth untouched. This research will allow communities to protect food chains and economies at home and in developing countries.”

By bringing together the best science and the brightest minds from around the globe, the initiative aims to generate workable solutions on the ground to improve animal welfare, productivity and ultimately enhance the lives of millions of people.

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Cold-water dip to raise funds for Vetlife

News Story 1
 The veterinary mental health charity Vetlife is inviting the veterinary community to join it for a sponsored cold-water dip.

The event will take place at Walpole Bay, Margate, on 17 May during Mental Health Awareness Week. Participants of all abilities can join in the challenge and are advised to bring a towel, a hot drink, a snack, and warm clothes to get changed into afterwards.

Those taking part are being asked to try to raise £100 each to support the work of the charity.

Details about how to take part can be found here

Click here for more...
News Shorts
Bluetongue low vector period ends

In an update to its bluetongue guidance, the Department for Environment, Food and Rural Affairs (Defra) has announced that the seasonal low vector period for the disease has ended.

With winter over, Defra is planning for a possible increase in cases as midges become more active. It has warned that farms along the east coast of England from Norfolk to Kent, and along the south coast from Kent to Devon, are at highest risk from infected midges blown over from northern Europe.

Since the virus was detected in England in November 2023, there have been 126 confirmed cases. The most recent case to be confirmed was on 1 March 2024.

Farmers are asked to continue to frequently monitor their livestock and ensure their animals and land are registered with the Animal and Plant Health Agency.